Product Name:

NebuSelect™ Recombinant Biotinylated Human IL-23 alpha&Mouse IL-12 beta, Avi-His-tag

Catalog#:

NBL-241279

Description:

NebuSelect™ Recombinant Biotinylated Human IL-23 alpha&Mouse IL-12 beta, Avi-His-tag(Cat#NBL-241279) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Arg20-Pro189 (Human IL-23 alpha) and Met23-Ser335 (Mouse IL-12 beta).

Species:

Human&Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 21.7 kDa (Human IL-23 alpha) & 35.8 kDa (Mouse IL-12 beta). Due to glycosylation, the protein migrates to 22-25 kDa (Human IL-23 alpha) & 45-60 kDa (Mouse IL-12 beta) based on Bis-Tris PAGE result.

Target Name:

IL-23 alpha&IL-12 beta

Target Information:

Interleukin (IL)-12 and IL-23 belong to the IL-12 type family and are composite cytokines, consisting of the common β subunit p40 and the specific cytokine α subunit p35 and p19, respectively. IL-12 signals via the IL-12Rβ1·IL-12Rβ2 receptor complex, and IL-23 uses also IL-12Rβ1 but engages IL-23R as second receptor.

Amino Acid Sequence: 

Arg20-Pro189(Human IL-23 alpha) & Met23-Ser335(Mouse IL-12 beta)

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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