Product Name:

NebuSelect™ Recombinant Human Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer, Avi-His-tag

Catalog#:

NBL-241305

Description:

NebuSelect™ Recombinant Human Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer, Avi-His-tag(Cat#NBL-241305) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val992 (ITGAV) acidic tail & Gln21-Asp728 (ITGB1) basic tail.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 114 kDa (ITGAV) and 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 130-160 kDa (ITGAV) and 100-120 kDa (ITGB1) based on Bis-Tris PAGE result.

Target Name:

Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer

Target Information:

Integrins are transmembrane heterodimeric receptors that contribute to diverse biological functions and play a conserved role in mediating cell adhesion to fixed extracellular ligands and in the maintenance of tissue integrity. αVβ1 is the major integrin on several different primary fibroblasts responsible for binding to TGFb1 LAP and for mediating activation of latent TGFb by these cells.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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