Product Name:

NebuSelect™ Recombinant Mouse CD8 alpha&beta Heterodimer, His-Flag-tag

Catalog#:

NBL-241398

Description:

NebuSelect™ Recombinant Mouse CD8 alpha&beta Heterodimer, His-Flag-tag(Cat#NBL-241398) is expressed in HEK293 with His tag and Flag tag at the C-terminus.It contains Lys28-Tyr196(CD8 alpha) acidic tail and Leu22-Thr175(CD8 beta) basic tail.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 24.80 kDa (CD8 alpha) and 23.17 kDa (CD8 beta). Due to glycosylation, the protein migrates to 32-38 kDa (CD8 alpha) and 42-50 kDa (CD8 beta) based on Bis-Tris PAGE result.

Target Name:

CD8 alpha&beta

Target Information:

CD8 alpha&beta (CD8αβ) is a heterodimeric form of CD8. CD8α is required for surface expression of CD8β. The extracellular IgV-like domain of CD8α interacts with the α3 portion of the class I MHC molecule. CD8αβ is expressed on human peripheral T cells and functions as a coreceptor and can greatly increase the sensitivity and breadth of antigen recognition by CD8+ peripheral T cells bearing TCR.

Amino Acid Sequence: 

Lys28-Tyr196(CD8 alpha) acidic tail & Leu22-Thr175(CD8 beta) basic tail

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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