Product Name:

NebuSelect™ Recombinant Canine CD40/TNFRSF5, His-tag

Catalog#:

NBL-241414

Description:

NebuSelect™ Recombinant Canine CD40/TNFRSF5, His-tag(Cat#NBL-241414) is expressed in HEK293 with His tag at the C-Terminus.It contains Glu21-Ala194.

Species:

Canine

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 20.14 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.

Target Name:

CD40/TNFRSF5

Target Information:

CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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