Product Name:

NebuSelect™ Recombinant Human Jagged 1/JAG1, His-tag

Catalog#:

NBL-241521

Description:

NebuSelect™ Recombinant Human Jagged 1/JAG1, His-tag(Cat#NBL-241521) is expressed in HEK293 with His tag at the C-Terminus.It contains Gln34-Ser1046.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 111.56 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on Bis-Tris PAGE result.

Target Name:

Jagged 1/JAG1

Target Information:

JAGGED1 (JAG1) is composed of a relatively small intracellular domain, a transmembrane domain and a larger extracellular component. JAG1 is widely expressed throughout mammalian development, across many tissues and developmental stages. The Notch signaling pathway and JAG1 in particular have been implicated in multiple forms of cancer and multiple aspects of cancer biology including tumor angiogenesis, neoplastic cell growth, cancer stem cell maintenance and the metastatic process.

Amino Acid Sequence: 

Gln34-Ser1046

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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