Product Name:

NebuSelect™ Recombinant Human PLVAP, His-tag

Catalog#:

NBL-241697

Description:

NebuSelect™ Recombinant Human PLVAP, His-tag(Cat#NBL-241697) is expressed in HEK293 with His tag at the N-Terminus.It contains Tyr49-Gly442.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 45.97 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.

Target Name:

PLVAP

Target Information:

Plasmalemma vesicle-associated protein (PLVAP, also called PV-1) is the only protein that forms endothelial diaphragms. PLVAP expression is very low in the normal blood-retinal barrier; however, pathological factors such as high glucose and vascular endothelial growth factor (VEGF) induce its expression, leading to the exacerbation of cellular permeability. Because the new blood vessels are fragile and leaky, PLVAP could possibly be considered a therapeutic target against retinovascular diseases.

Amino Acid Sequence: 

Tyr49-Gly442

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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