Product Name:

NebuSelect™ Recombinant Human GARP&Latent TGF Beta 2 Complex, Avi-His-tag

Catalog#:

NBL-241725

Description:

NebuSelect™ Recombinant Human GARP&Latent TGF Beta 2 Complex, Avi-His-tag(Cat#NBL-241725) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains His20-Leu628(GARP)&Leu21-Ser414(Latent TGF Beta 2).

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 70.3 kDa(GARP)&45.53 kDa(Latent TGF Beta 2). Due to enzyme lysis and glycosylation, the protein migrates to 72-77 kDa(GARP)&13 kDa&46-48 kDa(Latent TGF Beta 2) based on Bis-Tris PAGE result.

Target Name:

GARP&Latent TGF Beta 2 Complex

Target Information:

GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-β and thus promoting secretion and activation of TGF-β. Integrin αvβ8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the release of mature TGF-β from the TGF-β&GARP complex.

Amino Acid Sequence: 

His20-Leu628(GARP) & Leu21-Ser414(Latent TGF Beta 2)

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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