Product Name:

NebuSelect™ Recombinant Canine CD46, His-tag

Catalog#:

NBL-241750

Description:

NebuSelect™ Recombinant Canine CD46, His-tag(Cat#NBL-241750) is expressed in HEK293 with His tag at the C-Terminus.It contains Cys45-Gly344.

Species:

Canine

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 34.11 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.

Target Name:

CD46

Target Information:

CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'.

Amino Acid Sequence: 

Cys45-Gly344

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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