Product Name:

NebuSelect™ Recombinant Biotinylated Human IL-22R alpha 1&IL-10R beta, Avi-hFc-tag

Catalog#:

NBL-241809

Description:

NebuSelect™ Recombinant Biotinylated Human IL-22R alpha 1&IL-10R beta, Avi-hFc-tag(Cat#NBL-241809) is expressed in HEK293 with hFc tag and Avi Tag at the C-Terminus.It contains His16-Thr228 (IL-22R alpha 1) and Met20-Ser220 (IL-10R beta).

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 52.07 kDa (IL-22R alpha 1) and 48.85 kDa (IL-10R beta). Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result.

Target Name:

IL-22R alpha 1&IL-10R beta

Target Information:

IL-22Rα1&IL-10Rβ are receptors for IL-22 and IL-10, mediate the activation of JAK-STAT, MAPK and other signaling pathways, and participate in the process of many inflammatory diseases. IL­-22 Rα1 contains cytoplasmic motifs for interactions with signal transduction molecules, but formation of ternary complexes with IL­10 Rβ or IL­20 Rβ and the respective ligands is required for signal transduction[1].

Amino Acid Sequence: 

His16-Thr228(IL-22R alpha 1) & Met20-Ser220(IL-10R beta)

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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