Product Name:

NebuSelect™ Recombinant Biotinylated Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer, Avi-His-tag

Catalog#:

NBL-241908

Description:

NebuSelect™ Recombinant Biotinylated Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer, Avi-His-tag(Cat#NBL-241908) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val992(ITGAV) acidic tail & Glu43-Arg684(ITGB8) basic tail.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 114 kDa (ITGAV)&76 kDa (ITGB8) kDa. Due to glycosylation, the protein migrates to 85-145 kDa based on Bis-Tris PAGE result.

Target Name:

ITGAV&ITGB8

Target Information:

Deletions of the genes encoding the integrin αVβ8 (Itgav, Itgb8) have been shown to result in abnormal vascular development in the CNS, including prenatal and perinatal hemorrhage. Other work has indicated that a major function of this integrin in vivo is to promote TGFβ activation.

Amino Acid Sequence: 

Phe31-Val992(ITGAV) acidic tail & Glu43-Arg684(ITGB8) basic tail

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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