Product Name:

NebuSelect™ Recombinant Biotinylated Mouse PVRIG, Avi-hFc-tag

Catalog#:

NBL-241909

Description:

NebuSelect™ Recombinant Biotinylated Mouse PVRIG, Avi-hFc-tag(Cat#NBL-241909) is expressed in HEK293 with hFc tag and Avi tag at the C-Terminus.It contains Ser35-Asp165.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 42.7 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.

Target Name:

PVRIG

Target Information:

Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth.

Amino Acid Sequence: 

Ser35-Asp165

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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