Product Name:

NebuSelect™ Recombinant Human YKL-40/CHI3L1, His-tag

Catalog#:

NBL-241946

Description:

NebuSelect™ Recombinant Human YKL-40/CHI3L1, His-tag(Cat#NBL-241946) is expressed in HEK293 with His tag at the C-Terminus.It contains Tyr22-Thr383.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 41.6 kDa. Due to glycosylation, the protein migrates to 42-50 kDa based on Bis-Tris PAGE result.

Target Name:

YKL-40/CHI3L1; BRP39; CGP-39; GP-39; Chil1; ASRT7; FLJ38139; HC-gp39; YKL-40; YKL40; YYL-40; AW208766; CHI3L1; Chitinase 3 like 1

Target Information:

YKL-40 (also known as Chitinase 3-like 1) is a glycoprotein produced by inflammatory, cancer and stem cells. Its physiological role is not completely understood but YKL-40 is elevated in the brain and cerebrospinal fluid (CSF) in several neurological and neurodegenerative diseases associated with inflammatory processes. Yet the precise characterization of YKL-40 in dementia cases is missing. YKL-40 is a disease-specific marker of neuroinflammation showing its highest levels in prion diseases. Therefore, YKL-40 quantification might have a potential for application in the evaluation of therapeutic intervention in dementias with a neuroinflammatory component.

Amino Acid Sequence: 

Tyr22-Thr383

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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