Product Name:

NebuSelect™ Recombinant Mouse TSLPR, His-tag

Catalog#:

NBL-241972

Description:

NebuSelect™ Recombinant Mouse TSLPR, His-tag(Cat#NBL-241972) is expressed in HEK293 with His tag at the C-Terminus.It contains Ala20-Pro232.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 23.6 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Bis-Tris PAGE result.

Target Name:

TLSPR; TSLP receptor; TSLPR; CRL2; CRLF2Y; CRLF2; IL-XR; p2RY8/CRLF2 fusion; CRLF2

Target Information:

The pro-inflammatory cytokine thymic stromal lymphopoietin (TSLP) plays a pivotal role in the pathophysiology of various allergy disorders that are mediated by type 2 helper T cell (Th2) responses, such as asthma and atopic dermatitis. TSLP forms a ternary complex with the TSLP receptor (TSLPR) and the interleukin-7-receptor subunit alpha (IL-7Rα), thereby activating a signaling cascade that culminates in the release of pro-inflammatory mediators.

Amino Acid Sequence: 

Ala20-Pro232

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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