Product Name:

NebuSelect™ Recombinant Mouse Tim-3/HAVCR2, His-tag

Catalog#:

NBL-242010

Description:

NebuSelect™ Recombinant Mouse Tim-3/HAVCR2, His-tag(Cat#NBL-242010) is expressed in HEK293 with His tag at the C-Terminus.It contains Leu22-Arg191.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 19.9 kDa, Due to glycosylation, the protein migrates to 40-68 kDa based on Bis-Tris PAGE result.

Target Name:

Tim-3/HAVCR2; CD366; TIM3; TIM-3; TIMD-3; TIM 3;-FLJ14428; HAVCR2; KIM3

Target Information:

Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene.TIM3 is an immune checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3) mediate the CD8 T-cell exhaustion. TIM3 has also been shown as a CD4 Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.

Amino Acid Sequence: 

Leu22-Arg191

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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