Product Name:

NebuSelect™ Recombinant Human TGFBR1, Avi-mFc-tag

Catalog#:

NBL-242023

Description:

NebuSelect™ Recombinant Human TGFBR1, Avi-mFc-tag(Cat#NBL-242023) is expressed in HEK293 with mFc (IgG1) tag and Avi tag at the C-Terminus.It contains Leu34-Glu125.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 38.2 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Bis-Tris PAGE result.

Target Name:

TGFBR1; AAT5; ACVRLK4; ALK-5; LDS1A; LDS2A; SKR4; tbetaR-I; TGFB1R1; TGF-beta RI; TGFbetaRI; TGFBR1; TGF-bRI; TGFR-1

Target Information:

transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells.

Amino Acid Sequence: 

Leu34-Glu125

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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