Product Name:

NebuSelect™ Recombinant Human SIRP alpha/CD172a, hFc-tag

Catalog#:

NBL-242069

Description:

NebuSelect™ Recombinant Human SIRP alpha/CD172a, hFc-tag(Cat#NBL-242069) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Glu31-Arg370.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 64.1 kDa. Due to glycosylation, the protein migrates to 78-90 kDa based on Bis-Tris PAGE result.

Target Name:

SIRP alpha/CD172a; CD172a; BIT; MFR; MYD1; MYD-1; P84; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; SIRP alpha; SIRPA; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3

Target Information:

Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction.

Amino Acid Sequence: 

Glu31-Arg370

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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