Product Name:

NebuSelect™ Recombinant Mouse Siglec-5/CD170, His-tag

Catalog#:

NBL-242099

Description:

NebuSelect™ Recombinant Mouse Siglec-5/CD170, His-tag(Cat#NBL-242099) is expressed in HEK293 with His tag at the C-Terminus.It contains Thr17-Leu439.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 46.8 kDa. Due to glycosylation, the protein migrates to 65-68 kDa based on Bis-Tris PAGE result.

Target Name:

Siglec-5/CD170; CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2

Target Information:

Interactions between endothelial selectins and the leukocyte counter-receptor PSGL1 mediates leukocyte recruitment to inflammation sites. PSGL1 is highly sialylated, making it a potential ligand for Siglec-5, a leukocyte-receptor that recognizes sialic acid structures. Binding assays using soluble Siglec-5 variants (sSiglec-5/C4BP and sSiglec-5/Fc) revealed a dose- and calcium-dependent binding to PSGL1.

Amino Acid Sequence: 

Thr17-Leu439

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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