Product Name:

NebuSelect™ Recombinant Mouse RNF43, hFc-tag

Catalog#:

NBL-242159

Description:

NebuSelect™ Recombinant Mouse RNF43, hFc-tag(Cat#NBL-242159) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Gly24-Tyr197.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 45.6 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Bis-Tris PAGE result.

Target Name:

RNF34; E3 ubiquitin-protein ligase RNF43；RING finger protein 43；RING-type E3 ubiquitin transferase RNF43；Rnf43

Target Information:

RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the lysosomal pathway for degradation.

Amino Acid Sequence: 

Gly24-Tyr197

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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