Product Name:

NebuSelect™ Recombinant Human PD-1/PDCD1, mFc-tag

Catalog#:

NBL-242209

Description:

NebuSelect™ Recombinant Human PD-1/PDCD1, mFc-tag(Cat#NBL-242209) is expressed in HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Leu25-Gln167.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 41.6 kDa. Due to glycosylation, the protein migrates to 64-68 kDa based on Bis-Tris PAGE result.

Target Name:

PD-1/PDCD1; PDCD1; PD1; CD279; SLEB2; PD-1

Target Information:

Programmed Death-1 receptor (PD-1), also known as CD279, is type I transmembrane protein belonging to the CD28 family of immune regulatory receptors.PD1 is a inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell receptor (TCR) engagement, PDCD1 associates with CD3-TCR in the immunological synapse and directly inhibits T-cell activation.

Amino Acid Sequence: 

Leu25-Gln167

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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