Product Name:

NebuSelect™ Recombinant Human c-MPL/Thrombopoietin R, His-tag

Catalog#:

NBL-242292

Description:

NebuSelect™ Recombinant Human c-MPL/Thrombopoietin R, His-tag(Cat#NBL-242292) is expressed in HEK293 with His tag at the C-Terminus.It contains Gln26-Trp491.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 53.6 kDa. Due to glycosylation, the protein migrates to 68-70 kDa based on Bis-Tris PAGE result.

Target Name:

c-MPL/Thrombopoietin R; TPO-R; CD110; MPL; c-Mpl; MPLV; K12

Target Information:

The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of the c-mpl receptor chain. High levels of c-mpl expression were detected in 45% of acute myeloid leukemia (AML). No correlation was found between c-mpl expression and the French-American-British classification subtype of AML.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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