产品名称 | NebuSelect™ Recombinant Human HGF R/c-MET, hFc-tag |
---|---|
目录号 | NBL-242308 |
别名 | HGF R/c-MET; MET; oncogene MET; HGF R; HGF/SF receptor; AUTS9; cMET; Met (c-Met); RCCP2; SF receptor |
外观 | see COA |
分子量 | |
CAS | N/A |
溶解度 | Water Soluble |
存储条件 | Short term 4℃; Long term -20℃. |
保存时间 | 2 years |
备注1 | P08581-1 |
备注2 |
目录号 | 规格 | 价格 | 库存状态 | |
NBL-242308-100ug | 100ug | Inquire | Inquire | |
NBL-242308-1mg | 1mg | Inquire | Inquire | |
NBL-242308-Customized Size | N/A | Inquire | Inquire |
Product Name:
NebuSelect™ Recombinant Human HGF R/c-MET, hFc-tag
Catalog#:
NBL-242308
Description:
NebuSelect™ Recombinant Human HGF R/c-MET, hFc-tag(Cat#NBL-242308) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Glu25-Thr932.
Species:
Human
Expression System:
HEK293
Molecular Weight:
The mature form of HGF R is a heterodimer which can be cleaved into α and β chain. The protein has a predicted MW of 32.5 kDa (α chain) and 95.9 kDa (β chain Fc chimera). Due to glycosylation, the protein migrates to 45-55 kDa and 100-120 kDa based on Bis-Tris PAGE result.
Target Name:
HGF R/c-MET; MET; oncogene MET; HGF R; HGF/SF receptor; AUTS9; cMET; Met (c-Met); RCCP2; SF receptor
Target Information:
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGF R), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling.
Amino Acid Sequence:
Purity:
>95%
Formulation:
see COA
Endotoxin:
<1EU/ug(LAL Method)
Storage:
4°C for short term.
-20°C for long term.
To get more information, please contact us freely.