Product Name:

NebuSelect™ Recombinant Human LRP-5, mFc-tag

Catalog#:

NBL-242329

Description:

NebuSelect™ Recombinant Human LRP-5, mFc-tag(Cat#NBL-242329) is expressed in HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Glu644-Gln1263.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 96 kDa. Due to glycosylation, the protein migrates to 100-115 kDa based on Bis-Tris PAGE result.

Target Name:

LRP-5; LRP-5; LRP-7; LR3; BMND1; BMND1OPTA1; EVR1; EVR4; HBM; LR3VBCH2; LRP5; LRP7; OPPG; OPS; OPTA1; VBCH2

Target Information:

A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that altered the function of the sclerostin (SOST) gene were also associated with altered human bone mass. Subsequent studies of LRP5 and sclerostin have provided important insights into the mechanisms by which these proteins regulate skeletal homeostasis.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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