产品名称 | NebuSelect™ Recombinant Biotinylated Human LILRA4/CD85g, Avi-His-tag |
---|---|
目录号 | NBL-242350 |
别名 | LILRA4/CD85g; CD85g; ILT7; ILT-7; ILT7MGC129598; LILRA4; MGC129597 |
外观 | see COA |
分子量 | Glu24-Asn446 |
CAS | N/A |
溶解度 | Water Soluble |
存储条件 | Short term 4℃; Long term -20℃. |
保存时间 | 2 years |
备注1 | P59901 |
备注2 |
目录号 | 规格 | 价格 | 库存状态 | |
NBL-242350-100ug | 100ug | Inquire | Inquire | |
NBL-242350-1mg | 1mg | Inquire | Inquire | |
NBL-242350-Customized Size | N/A | Inquire | Inquire |
Product Name:
NebuSelect™ Recombinant Biotinylated Human LILRA4/CD85g, Avi-His-tag
Catalog#:
NBL-242350
Description:
NebuSelect™ Recombinant Biotinylated Human LILRA4/CD85g, Avi-His-tag(Cat#NBL-242350) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu24-Asn446.
Species:
Human
Expression System:
HEK293
Molecular Weight:
The protein has a predicted MW of 49.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Target Name:
LILRA4/CD85g; CD85g; ILT7; ILT-7; ILT7MGC129598; LILRA4; MGC129597
Target Information:
LILRA4, also known as ILT7 and CD85g, is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains, a 21 aa transmembrane segment, and a 32 aa cytoplasmic domain.LILRA4 function coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades.
Amino Acid Sequence:
Glu24-Asn446
Purity:
>95%
Formulation:
see COA
Endotoxin:
<1EU/ug(LAL Method)
Storage:
4°C for short term.
-20°C for long term.
To get more information, please contact us freely.