Product Name:

NebuSelect™ Recombinant Human KIR2DL3, Avi-His-tag

Catalog#:

NBL-242403

Description:

NebuSelect™ Recombinant Human KIR2DL3, Avi-His-tag(Cat#NBL-242403) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 27.3 kDa. Due to glycosylation, the protein migrates to 45-52 kDa based on Bis-Tris PAGE result.

Target Name:

KIR2DL3; cl-6; KIR2DL3; KIRCL23; KIR-K7b; KIR-K7c; MGC129943; NKAT; NKAT2; NKAT-2; NKAT2A; NK-receptor; p58; NKAT2GL183; CD158b; CD158B2; GL183; KIR-023GB; KIR2DS5; NKAT2B

Target Information:

KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family of molecules. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.

Amino Acid Sequence: 

His22-His245

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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