产品名称 | NebuSelect™ Recombinant Human Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer, His-tag |
---|---|
目录号 | NBL-242423 |
别名 | Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer; Integrin alpha A1 beta 1; alpha A1 beta 1; alpha A1; beta 1; ITGA1&ITGB1; ITGA&ITGB |
外观 | see COA |
分子量 | Phe29-Pro1141(ITGA1) acidic tail & Gln21-Asp728(ITGB1) basic tail |
CAS | N/A |
溶解度 | Water Soluble |
存储条件 | Short term 4℃; Long term -20℃. |
保存时间 | 2 years |
备注1 | P56199-1(ITGA1)&P05556-1(ITGB1) |
备注2 |
目录号 | 规格 | 价格 | 库存状态 | |
NBL-242423-100ug | 100ug | Inquire | Inquire | |
NBL-242423-1mg | 1mg | Inquire | Inquire | |
NBL-242423-Customized Size | N/A | Inquire | Inquire |
Product Name:
NebuSelect™ Recombinant Human Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer, His-tag
Catalog#:
NBL-242423
Description:
NebuSelect™ Recombinant Human Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer, His-tag(Cat#NBL-242423) is expressed in HEK293 with His tag at the C-Terminus.It contains Phe29-Pro1141(ITGA1) acidic tail & Gln21-Asp728(ITGB1) basic tail.
Species:
Human
Expression System:
HEK293
Molecular Weight:
The protein has a predicted MW of 129.1 kDa(ITGA1)&83.2 kDa(ITGB1). Due to glycosylation, the protein migrates to 160-200 kDa based on Bis-Tris PAGE result.
Target Name:
Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer; Integrin alpha A1 beta 1; alpha A1 beta 1; alpha A1; beta 1; ITGA1&ITGB1; ITGA&ITGB
Target Information:
Integrin α1β1 is a heterodimer of the Integrin subunits alpha 1 and beta 1 and is one of four collagen‑binding integrins, it preferentially binds Collagens I, IV, VI, XIII and XVI, but also binds Laminin. Integrin α1β1 is widely expressed in mesenchyme and the immune system, as well as a minority of epithelial tissues. It can suppresse EGFR signaling, increase expression of Caveolin-1, reduce production of reactive oxygen species, regulate collagen expression, regulate MMP collagenase and gelatinase activity, and mediates the renal basement membrane disorder Alport syndrome.
Amino Acid Sequence:
Phe29-Pro1141(ITGA1) acidic tail & Gln21-Asp728(ITGB1) basic tail
Purity:
>95%
Formulation:
see COA
Endotoxin:
<1EU/ug(LAL Method)
Storage:
4°C for short term.
-20°C for long term.
To get more information, please contact us freely.