产品名称 | NebuSelect™ Recombinant Human IL-2 R beta&IL-2 R gamma, hFc-tag |
---|---|
目录号 | NBL-242434 |
别名 | IL-2 R beta&IL-2 R gamma; IL-2RB&IL-2RG; IL-2RG; IL-2R subunit gamma; IL-2R subunit beta; IL-2RB; IL15RB; IL-2 R beta&IL-2 R gamma |
外观 | see COA |
分子量 | |
CAS | N/A |
溶解度 | Water Soluble |
存储条件 | Short term 4℃; Long term -20℃. |
保存时间 | 2 years |
备注1 | P14784(IL-2 R beta)&P31785-1(IL-2 R gamma) |
备注2 |
目录号 | 规格 | 价格 | 库存状态 | |
NBL-242434-100ug | 100ug | Inquire | Inquire | |
NBL-242434-1mg | 1mg | Inquire | Inquire | |
NBL-242434-Customized Size | N/A | Inquire | Inquire |
Product Name:
NebuSelect™ Recombinant Human IL-2 R beta&IL-2 R gamma, hFc-tag
Catalog#:
NBL-242434
Description:
NebuSelect™ Recombinant Human IL-2 R beta&IL-2 R gamma, hFc-tag(Cat#NBL-242434) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Ala27-Thr240 (IL-2 R beta)&Leu23-Ala262 (IL-2 R gamma).
Species:
Human
Expression System:
HEK293
Molecular Weight:
The protein has a predicted MW of 51.3 kDa (IL-2 R beta)&54.6 kDa (IL-2 R gamma). Due to glycosylation, the protein migrates to 65-70 kDa&80-100 kDa based on Bis-Tris PAGE result.
Target Name:
IL-2 R beta&IL-2 R gamma; IL-2RB&IL-2RG; IL-2RG; IL-2R subunit gamma; IL-2R subunit beta; IL-2RB; IL15RB; IL-2 R beta&IL-2 R gamma
Target Information:
Wilms' tumor 1 (WT1) is a transcription factor which plays a major role in cell proliferation, differentiation, survival, and apoptosis. WT1 was first identified as a tumor suppressor gene in Wilms' tumor. The expression of survival signaling genes, IL-2, IL-2RB, and IL-2RG, was also suppressed after WT1-siRNA treatment. In addition, the WT1 silencing also inhibited the S phase of the cell cycle and induced cell death.Moreover, transcriptional modulation of IL-2, IL-2RB, and IL2-2RG expression by WT1 was likely involved in this phenotypic change.
Amino Acid Sequence:
Purity:
>95%
Formulation:
see COA
Endotoxin:
<1EU/ug(LAL Method)
Storage:
4°C for short term.
-20°C for long term.
To get more information, please contact us freely.