Product Name:

NebuSelect™ Recombinant Biotinylated Human IL-1R3/IL-1 RAcP, Avi-His-tag

Catalog#:

NBL-242496

Description:

NebuSelect™ Recombinant Biotinylated Human IL-1R3/IL-1 RAcP, Avi-His-tag(Cat#NBL-242496) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Ser21-Glu359.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 42 kDa. Due to glycosylation, the protein migrates to 52-70 kDa based on Bis-Tris PAGE result.

Target Name:

IL-1R3/IL-1 RAcP; IL1RAP; C3orf13; IL-1 R3; IL-1 RAcP

Target Information:

IL-1 Receptor Accessory Protein (IL-1 RAcP), also known as IL-1 R3, is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the receptors for IL-1 alpha, IL-1 beta, IL-33, and IL-36. IL-1 R3 is a coreceptor for IL1RL2 in the IL-36 signaling system. IL-1 R3 is a coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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