Product Name:

NebuSelect™ Recombinant Human ICOS/CD278, hFc-tag

Catalog#:

NBL-242535

Description:

NebuSelect™ Recombinant Human ICOS/CD278, hFc-tag(Cat#NBL-242535) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Glu21-Phe141.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 40.5 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result.

Target Name:

ICOS/CD278; AILIM; CD278; CRP-1; CVID1; ICOS; MGC39850

Target Information:

Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. Human ICOS is a homodimeric type I transmembrane protein consisting of 199 amino acids (aa) with a putative 20 aa signal sequence, a 121 aa extracellular domain, a 23 aa transmembrane region, and a 35 aa cytoplasmic domain.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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