产品名称 | NebuSelect™ Recombinant Mouse GEP, His-tag |
---|---|
目录号 | NBL-242592 |
别名 | GEP; Progranulin; PGRN; Acrogranin; GP88; Glycoprotein 88; PCDGF; PEPI; CLN11; GEP; Granulin; GRN |
外观 | see COA |
分子量 | Thr18-Leu589 |
CAS | N/A |
溶解度 | Water Soluble |
存储条件 | Short term 4℃; Long term -20℃. |
保存时间 | 2 years |
备注1 | P28798 |
备注2 |
目录号 | 规格 | 价格 | 库存状态 | |
NBL-242592-100ug | 100ug | Inquire | Inquire | |
NBL-242592-1mg | 1mg | Inquire | Inquire | |
NBL-242592-Customized Size | N/A | Inquire | Inquire |
Product Name:
NebuSelect™ Recombinant Mouse GEP, His-tag
Catalog#:
NBL-242592
Description:
NebuSelect™ Recombinant Mouse GEP, His-tag(Cat#NBL-242592) is expressed in HEK293 with His tag at the C-Terminus.It contains Thr18-Leu589.
Species:
Mouse
Expression System:
HEK293
Molecular Weight:
The protein has a predicted MW of 62.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Target Name:
GEP; Progranulin; PGRN; Acrogranin; GP88; Glycoprotein 88; PCDGF; PEPI; CLN11; GEP; Granulin; GRN
Target Information:
Haploinsufficiency of progranulin (PGRN) is a leading cause of frontotemporal lobar degeneration (FTLD). Loss of PGRN leads to lysosome dysfunction during aging. TMEM106B, a gene encoding a lysosomal membrane protein, is the main risk factor for FTLD with PGRN haploinsufficiency.Loss of both PGRN and TMEM106B results in an increased accumulation of lysosomal vacuoles in the axon initial segment of motor neurons and enhances the manifestation of FTLD phenotypes with a much earlier onset.
Amino Acid Sequence:
Thr18-Leu589
Purity:
>95%
Formulation:
see COA
Endotoxin:
<1EU/ug(LAL Method)
Storage:
4°C for short term.
-20°C for long term.
To get more information, please contact us freely.