Product Name:

NebuSelect™ Recombinant Human FGFR4, Avi-His-tag

Catalog#:

NBL-242659

Description:

NebuSelect™ Recombinant Human FGFR4, Avi-His-tag(Cat#NBL-242659) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Leu22-Asp369.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 41.4 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.

Target Name:

FGFR4; CD334; FGF R4; FGFR4; FGFR-4; MGC20292; JTK2; TKF

Target Information:

Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19.

Amino Acid Sequence: 

Leu22-Asp369

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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