产品名称 | NebuSelect™ Recombinant Mouse EREG, hFc-tag |
---|---|
目录号 | NBL-242700 |
别名 | EREG; Proepiregulin; EPR; Epiregulin; EREG; ER |
外观 | see COA |
分子量 | Val56-Leu101 |
CAS | N/A |
溶解度 | Water Soluble |
存储条件 | Short term 4℃; Long term -20℃. |
保存时间 | 2 years |
备注1 | Q61521 |
备注2 |
目录号 | 规格 | 价格 | 库存状态 | |
NBL-242700-100ug | 100ug | Inquire | Inquire | |
NBL-242700-1mg | 1mg | Inquire | Inquire | |
NBL-242700-Customized Size | N/A | Inquire | Inquire |
Product Name:
NebuSelect™ Recombinant Mouse EREG, hFc-tag
Catalog#:
NBL-242700
Description:
NebuSelect™ Recombinant Mouse EREG, hFc-tag(Cat#NBL-242700) is expressed in HEK293 with hFc tag at the N-Terminus.It contains Val56-Leu101.
Species:
Mouse
Expression System:
HEK293
Molecular Weight:
The protein has a predicted MW of 32.7 kDa. Due to glycosylation, the protein migrates to 37-40 kDa based on Bis-Tris PAGE result.
Target Name:
EREG; Proepiregulin; EPR; Epiregulin; EREG; ER
Target Information:
Epidermal growth factor receptor (EGFR) regulates many crucial cellular programs, with seven different activating ligands shaping cell signaling in distinct ways.EGFR ligands epiregulin (EREG) and epigen (EPGN) stabilize different dimeric conformations of the EGFR extracellular region. As a consequence, EREG or EPGN induce less stable EGFR dimers than EGF-making them partial agonists of EGFR dimerization. Unexpectedly, this weakened dimerization elicits more sustained EGFR signaling than seen with EGF, provoking responses in breast cancer cells associated with differentiation rather than proliferation.
Amino Acid Sequence:
Val56-Leu101
Purity:
>95%
Formulation:
see COA
Endotoxin:
<1EU/ug(LAL Method)
Storage:
4°C for short term.
-20°C for long term.
To get more information, please contact us freely.