Product Name:

NebuSelect™ Recombinant Human CTLA-4/CD152, hFc-tag

Catalog#:

NBL-242760

Description:

NebuSelect™ Recombinant Human CTLA-4/CD152, hFc-tag(Cat#NBL-242760) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Lys36-Asp161.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 40.1 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Bis-Tris PAGE result.

Target Name:

CTLA-4/CD152; CTLA4; CD152; ICOS; CELIAC3; GRD4; GSE; ALPS5; IDDM12

Target Information:

CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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