Product Name:

NebuSelect™ Recombinant Human M-CSF R/CSF1R/CD115, hFc-tag

Catalog#:

NBL-242766

Description:

NebuSelect™ Recombinant Human M-CSF R/CSF1R/CD115, hFc-tag(Cat#NBL-242766) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Ile20-Glu512.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 81.3 kDa. Due to glycosylation, the protein migrates to 100-130 kDa based on Bis-Tris PAGE result.

Target Name:

M-CSF R/CSF1R/CD115; CD115; CSF1R; CSF-1-R; CSFR; FMSFIM2; M-CSF R; MCSFR; M-CSFR; C-FMS; FIM2; FMS; HDLS

Target Information:

CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region.CSF1R is tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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