Product Name:

NebuSelect™ Recombinant Biotinylated SARS-COV-2 Spike S (Omicron B.1.1.529) Trimer, Avi-His-tag

Catalog#:

NBL-242781

Description:

NebuSelect™ Recombinant Biotinylated SARS-COV-2 Spike S (Omicron B.1.1.529) Trimer, Avi-His-tag(Cat#NBL-242781) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Val16-Pro1213(A67V, HV69-70del, T95I, G142D, VYY143-145del, N211del, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.

Species:

SARS-COV-2

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 136.70 kDa. Due to glycosylation, the protein migrates to 140-180 kDa based on Bis-Tris PAGE result.

Target Name:

Spike S (Omicron B.1.1.529) Trimer; S protein; Spike glycoprotein; S glycoprotein; COVID-19

Target Information:

The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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