Product Name:

NebuSelect™ Recombinant Mouse Clusterin, His-tag

Catalog#:

NBL-242797

Description:

NebuSelect™ Recombinant Mouse Clusterin, His-tag(Cat#NBL-242797) is expressed in HEK293 with His tag at the C-Terminus.It contains Glu22-Glu448.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 50.4 kDa. Due to autocatalytic cleavage, the protein migrates to 35-40 kDa and 43-50 kDa based on Bis-Tris PAGE result.

Target Name:

Clusterin; Clusterin; Apolipoprotein J; Apo-J; Clustrin; SGP-2; Msgp-2; CLU; AAG4; APOJ; CLI; KUB1; SP-40; TRPM2; CLI; CLU1; CLU2; KUB1; NA1/NA2; KUB1SGP2; MGC24903

Target Information:

Clusterin (CLU) is a stress-activated, ATP-independent molecular chaperone, normally secreted from cells, that is up-regulated in Alzheimer disease and in many cancers. It plays important roles in protein homeostasis/proteostasis, inhibition of cell death pathways, and modulation of pro-survival signalling and transcriptional networks. Changes in the CLU gene locus are highly associated with Alzheimer disease, and many therapy-resistant cancers over-express CLU.

Amino Acid Sequence: 

Glu22-Glu448

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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