Product Name:

NebuSelect™ Recombinant Mouse MDL-1/CLEC5A, hFc-tag

Catalog#:

NBL-242799

Description:

NebuSelect™ Recombinant Mouse MDL-1/CLEC5A, hFc-tag(Cat#NBL-242799) is expressed in HEK293 with hFc tag at the N-Terminus.It contains Tyr26-Lys190.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 46.2 kDa. Due to glycosylation, the protein migrates to 64-68 kDa based on Bis-Tris PAGE result.

Target Name:

MDL-1/CLEC5A; MDL-1; CLECSF5; MDL1; CLEC5A; DAP12-associating lectin 1

Target Information:

In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality.

Amino Acid Sequence: 

Tyr26-Lys190

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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