Product Name:

NebuSelect™ Recombinant Mouse Complement Factor D/CFD, hFc-tag

Catalog#:

NBL-242815

Description:

NebuSelect™ Recombinant Mouse Complement Factor D/CFD, hFc-tag(Cat#NBL-242815) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Ile26-Ser259.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 52.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Target Name:

Complement Factor D/CFD; Adipsin; C3 convertase activator; Complement factor D; CFD; PFD; DF; ADN; FACTOR D; AMBP-1; EC 3.4.21; EC 3.4.21.46

Target Information:

Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.

Amino Acid Sequence: 

Ile26-Ser259

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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