Product Name:

NebuSelect™ Recombinant Human CD96/TACTILE, mFc-tag

Catalog#:

NBL-242852

Description:

NebuSelect™ Recombinant Human CD96/TACTILE, mFc-tag(Cat#NBL-242852) is expressed in HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Val22-Met503.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 79.8 kDa. Due to glycosylation, the protein migrates to 120-160 kDa based on Bis-Tris PAGE result.

Target Name:

CD96/TACTILE; CD96 molecule; CD96; DKFZp667E2122; TACTILE

Target Information:

The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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