Product Name:

NebuSelect™ Recombinant Human CD37, hFc-tag

Catalog#:

NBL-242923

Description:

NebuSelect™ Recombinant Human CD37, hFc-tag(Cat#NBL-242923) is expressed in HEK293 with hFc tag at the N-Terminus.It contains Ala113-Asn240.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 41.9 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

Target Name:

CD37; Tetraspanin-26; Tspan-26; CD37; CD37 molecule; GP52-40; MGC120234

Target Information:

CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients.

Amino Acid Sequence: 

Ala113-Asn240

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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