Product Name:

NebuSelect™ Recombinant Human BDCA-2, hFc-tag

Catalog#:

NBL-243046

Description:

NebuSelect™ Recombinant Human BDCA-2, hFc-tag(Cat#NBL-243046) is expressed in HEK293 with hFc tag at the N-Terminus; It contains Phe46-Ile213.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 47.1 kDa. Due to glycosylation, the protein migrates to 60-66 kDa based on Bis-Tris PAGE result.

Target Name:

BDCA-2; BDCA-2; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; CLEC4C; CD303; BDCA2MGC125791; CD303; CLECSF11PRO34150; DLEC; DLECMGC125792; HECLMGC125793; MGC125789; PRO34150

Target Information:

BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three Ags are not detectable on a third blood dendritic cell population, which is CD1c() CD11c(bright) CD123(dim), or on any other cells in blood.BDCA-2 is completely down-regulated on plasmacytoid CD11c(-) CD123(bright) dendritic cells, BDCA-2 is rapidly internalized at 37 degrees C after mAb labeling.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

To get more information, please contact us freely.