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产品名称 NebuSelect™ Recombinant Human AMIGO2, His-tag
目录号 NBL-243112
别名 AMIGO2; Amphotein-induced protein 2; AMIGO-2; Alivin-1; DEGA; AMIGO2; ALI1; alivin 1
外观 see COA
分子量 Val40-Thr398
CAS N/A
溶解度 Water Soluble
存储条件 Short term 4℃; Long term -20℃.
保存时间 2 years
备注1 Q86SJ2
备注2
目录号 规格 价格 库存状态  
NBL-243112-100ug 100ug Inquire Inquire
NBL-243112-1mg 1mg Inquire Inquire
NBL-243112-Customized Size N/A Inquire Inquire


Product Name:

NebuSelect™ Recombinant Human AMIGO2, His-tag


Catalog#:

NBL-243112


Description:

NebuSelect™ Recombinant Human AMIGO2, His-tag(Cat#NBL-243112) is expressed in HEK293 with His tag at the C-Terminus.It contains Val40-Thr398.


Species:

Human


Expression System:

HEK293


Molecular Weight: 

The protein has a predicted MW of 42 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.


Target Name:

AMIGO2; Amphotein-induced protein 2; AMIGO-2; Alivin-1; DEGA; AMIGO2; ALI1; alivin 1


Target Information:

Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic melanoma, yet their mechanism of action remains unclear. Here we interrogated the transcriptional effects of BETi and identified AMIGO2, a transmembrane molecule, as a BET target gene essential for melanoma cell survival. AMIGO2 is upregulated in melanoma cells and tissues compared to human melanocytes and nevi, and AMIGO2 silencing in melanoma cells induces G1/S arrest followed by apoptosis.


Amino Acid Sequence: 

Val40-Thr398


Purity:

>95%


Formulation:

see COA


Endotoxin:

<1EU/ug(LAL Method)


Storage: 

4°C for short term. 

-20°C for long term.


To get more information, please contact us freely.

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