Product Name:

NebuSelect™ Recombinant Rat PDGF-AA, His-tag

Catalog#:

NBL-243145

Description:

NebuSelect™ Recombinant Rat PDGF-AA, His-tag(Cat#NBL-243145) is expressed in Yeast with His tag at the N-terminus.It contains Arg86-Lys204.

Species:

Rat

Expression System:

Yeast

Molecular Weight: 

The protein has a predicted MW of 14.75 kDa. Due to glycosylation, the protein migrates to 17-22 kDa and 25-45 kDa based on Bis-Tris PAGE result.

Target Name:

PDGF-AA

Target Information:

PDGF (Platelet-derived growth factor) is one among numerous growth factors that regulate cell growth and division. The PDGF family forms five dimeric ligands, PDGF-AA, PDGF-BB, PDGF-CC, PDGF-DD, and PDGF-AB, which activate cognate receptor tyrosine kinases PDGFR-α and PDGFR-β. Upon binding to its tyrosine kinase receptor PDGF-αα, PDGF-AA stimulates the proliferation of osteoblastic cells and may exert autocrine and paracrine effects in regulating bone-forming processes. PDGF-AA is the most well characterized mitogen that is not restricted to any kind of tumor cell type but was seen in osteoblastic cells as well as in pleomorphic tumor elements.

Amino Acid Sequence: 

Arg86-Lys204

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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