辰辉创聚生物®Nebulabio 在肿瘤免疫治疗和抗体药物开发领域具有深厚技术积累和独特优势,在免疫检查点抑制剂、单克隆抗体以及双特异性抗体等方面积累了丰富的经验。
早在20世纪初,保罗·埃尔利希首次提出了“魔法子弹”的概念,并假设某些化合物可以直接作用于细胞中的某些期望靶标以治疗疾病。理论上,这些化合物应该能有效杀死癌细胞,但对正常细胞无害。一种可行的方法是识别一些在癌细胞上特异性高表达的抗原,以区分癌细胞和健康细胞,如乳腺癌上的HER2(人类表皮生长因子受体2)和B细胞淋巴瘤上的CD20(分化簇20)。这些抗原的特异性表达为通过单克隆抗体(mAbs)精确靶向肿瘤提供了可能性,自1975年杂交瘤技术发展以来,这一领域取得了巨大进步。近几十年来,越来越多的mAbs,如阿瓦斯汀、曲妥珠单抗、利妥昔单抗和小细胞肺癌,已在全球范围内获得批准,用于治疗各种实体瘤和血液癌症。
系列产品列表:
目录号 | 品名 | 产品描述 | 特异性 | 抗体类型 |
NBAB-100419 | NebuSelect™ Anti-Alpha-fetoprotein Monoclonal Antibody | Alpha-fetoprotein | Human | Mouse MAb |
NBAB-101972 | NebuSelect™ Recombinant Anti-CD19 Monoclonal Antibody | CD19 | Mouse | Rabbit MAb |
NBAB-102214 | NebuSelect™ Anti-CD28 Monoclonal Antibody | CD28 | Rat | Mouse MAb |
NBAB-102433 | NebuSelect™ Anti-CD40/TNFRSF5 Monoclonal Antibody | CD40; TNFRSF5 | Rat | Mouse MAb |
NBAB-102439 | NebuSelect™ Anti-CD40 Ligand/TNFSF5 Monoclonal Antibody | CD40 Ligand; TNFSF5 | Human | Mouse MAb |
NBAB-102736 | NebuSelect™ Anti-CD70/CD27 Ligand Polyclonal Antibody | CD70; CD27 | Mouse | Rabbit PAb |
NBAB-102876 | NebuSelect™ Recombinant Anti-B7-2/CD86 Monoclonal Antibody | B7-2; CD86 | Cynomolgus; Rhesus | Rabbit MAb |
NBAB-103009 | NebuSelect™ Anti-CDK4 Polyclonal Antibody | CDK4 | Human | Rabbit PAb |
NBAB-103086 | NebuSelect™ Recombinant Anti-CEACAM-5/CD66e Monoclonal Antibody | CEACAM-5; CD66e | Human | Rabbit MAb |
NBAB-103968 | NebuSelect™ Anti-CTLA-4 Polyclonal Antibody | CTLA-4 | Canine | Rabbit PAb |
NBAB-104123 | NebuSelect™ Recombinant Anti-IL-8/CXCL8 Monoclonal Antibody | IL-8; CXCL8 | Rhesus | Rabbit MAb |
NBAB-108257 | NebuSelect™ Recombinant Anti-VEGFR2/KDR Monoclonal Antibody | VEGFR2; KDR | Rat | Rabbit MAb |
NBAB-108438 | NebuSelect™ Anti-KRAS Polyclonal Antibody | KRAS | Human | Rabbit PAb |
NBAB-108535 | NebuSelect™ Anti-LAG-3 Polyclonal Antibody | LAG-3 | Mouse | Rabbit PAb |
关键词:
Alpha-fetoprotein抗体,CD19抗体,CD28抗体,CD40抗体,CD40L抗体,CD70抗体,B7-2抗体,CDK4抗体,CEACAM-5抗体,CTLA-4抗体,IL-8抗体,VEGFR2抗体,KRAS抗体,LAG-3抗体,TNFRSF5抗体,TNFSF5抗体,CD27抗体,CD86抗体,CD66e抗体,CXCL8抗体,KDR抗体,Anti-Alpha-fetoprotein,Anti-CD19,Anti-CD28,Anti-CD40,Anti-CD40L,Anti-CD70,Anti-B7-2,Anti-CDK4,Anti-CEACAM-5,Anti-CTLA-4,Anti-IL-8,Anti-VEGFR2,Anti-KRAS,Anti-LAG-3,Anti-TNFRSF5,Anti-TNFSF5,Anti-CD27,Anti-CD86,Anti-CD66e,Anti-CXCL8,Anti-KDR,抗Alpha-fetoprotein单抗,抗CD19单抗,抗CD28单抗,抗CD40单抗,抗CD40L单抗,抗CD70单抗,抗B7-2单抗,抗CDK4单抗,抗CEACAM-5单抗,抗CTLA-4单抗,抗IL-8单抗,抗VEGFR2单抗,抗KRAS单抗,抗LAG-3单抗,抗TNFRSF5单抗,抗TNFSF5单抗,抗CD27单抗,抗CD86单抗,抗CD66e单抗,抗CXCL8单抗,抗KDR单抗