致力于药物研发关键试剂的生产

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辰辉创聚生物®Nebulabio 提供抗体偶联药物(antibody-drugconjugate, ADC)


辰辉创聚生物®Nebulabio 深耕 ADC 小分子领域多年,主要提供 ADC 药物小分子以及 ADC 偶联定制服务,拥有 80多种库存现货产品。

ADC药物是采用特定的连接子将抗体和小分子细胞毒药物连接起来,其主要组成成分包括 抗体、连接子和小分子细胞毒药物(smallmolecular cytotoxic drug,SM)。抗体分子主要发挥靶向投递 作用,小分子药物发挥效应。但有些抗体同时存在 抗肿瘤的药效学作用,如Kadcyla中阿多曲妥珠单抗(ado-trastuzumab)和美坦新(maitansine)(美登素)存在协同作用。


Antibody-drug_conjugate_structure.svg.png

系列产品列表如下:

目录号品名物种靶点表达细胞系
NBR-1000NebuSelect™ Anti-ALCAM / CD166 Reference Antibody (Praluzatamab-MMAE)HumanALCAM / CD166CHO
NBR-1001NebuSelect™ Anti-AMHR2 Reference Antibody (Murlentamab-MMAE)HumanAMHR2CHO
NBR-1002NebuSelect™ Anti-AXL / UFO Reference Antibody (Enapotamab vedotin)HumanAXL / UFOCHO
NBR-1003NebuSelect™ Anti-AXL / UFO Reference Antibody (Tilvestamab-MMAE)HumanAXL / UFOCHO
NBR-1004NebuSelect™ Anti-MUC16 Reference Antibody (oregovomab-MMAE)HumanCA125 / MUC16CHO
NBR-1005NebuSelect™ Anti-MUC16 Reference Antibody (Sofituzumab vedotin)HumanCA125 / MUC16CHO
NBR-1006NebuSelect™ Anti-CA9 / CAIX Reference Antibody (girentuximab-MMAE)HumanCA9 / Carbonic anhydrase 9CHO
NBR-1007NebuSelect™ Anti-CD19 Reference Antibody (denintuzumab-MMAF)HumanCD19CHO
NBR-1008NebuSelect™ Anti-CD79b Reference Antibody (Polatuzumab vedotin-piiq)HumanCD79bCHO
NBR-1009NebuSelect™ Anti-CD79b Reference Antibody (iladatuzumab vedotin)HumanCD79bCHO
NBR-1010NebuSelect™ Anti-CEACAM5 / CEA / CD66e Reference Antibody (labetuzumab govitecan)HumanCEACAM5 / CEA / CD66eCHO
NBR-1011NebuSelect™ Anti-CEACAM5 / CEA / CD66e Reference Antibody (Tusamitamab-MMAE)HumanCEACAM5 / CEA / CD66eCHO
NBR-1012NebuSelect™ Anti-CLDN18.2 Reference Antibody (zolbetuximab MMAE)HumanCLDN18.2CHO
NBR-1013NebuSelect™ Anti-CXCR4/CD184 Reference Antibody (ulocuplumab-MMAE)HumanCXCR4 / CD184CHO
NBR-1014NebuSelect™ Anti-DLL3 Reference Antibody (rovalpituzumab-MMAE)HumanDLL3CHO
NBR-1015NebuSelect™ Anti-Endoglin / CD105 Reference Antibody (carotuximab-MMAE)HumanEndoglin / CD105CHO
NBR-1016NebuSelect™ Anti-ERBB1 / EGFR / HER1 Reference Antibody (depatuxizumab-MMAF)HumanERBB1 / EGFR / HER1CHO
NBR-1017NebuSelect™ Anti-ERBB1 / EGFR / HER1 Reference Antibody (Cetuximab-MMAE)HumanERBB1 / EGFR / HER1CHO
NBR-1018NebuSelect™ Anti-ERBB2 / HER2 / CD340 Reference Antibody (Disitamab vedotin)HumanERBB2 / HER2 / CD340CHO
NBR-1019NebuSelect™ Anti-ERBB2 / HER2 / CD340 Reference Antibody (Trastuzumab-MMAE)HumanERBB2 / HER2 / CD340CHO
NBR-1020NebuSelect™ Anti-ERBB3/ HER3 Reference Antibody (patritumab-MMAE)HumanERBB3 / HER3CHO
NBR-1021NebuSelect™ Anti-ERBB3/ HER3 Reference Antibody (Patritumab deruxtecan)HumanERBB3 / HER3CHO
NBR-1022NebuSelect™ Anti-FOLH1 / PSMA Reference Antibody (rosopatamab-MMAE)HumanFOLH1 / PSMACHO
NBR-1023NebuSelect™ Anti-FOLR1 / FRA Reference Antibody (farletuzumab-MMAE)HumanFOLR1 / FRACHO
NBR-1024NebuSelect™ Anti-FOLR1 / FRA Reference Antibody (mirvetuximab-MMAE)HumanFOLR1 / FRACHO
NBR-1025NebuSelect™ Anti-GD3 Reference Antibody (ecromeximab-MMAE)HumanGD3CHO
NBR-1026NebuSelect™ Anti-GPC3 / Glypican-3 Reference Antibody (Codrituzumab-MMAE)HumanGPC3 / Glypican-3CHO
NBR-1027NebuSelect™ Anti-GPNMB Reference Antibody (Glembatumumab vedotin)HumanGPNMBCHO
NBR-1028NebuSelect™ Anti-GUCY2C Reference Antibody (Indusatumab vedotin)HumanGUCY2CCHO
NBR-1029NebuSelect™ Anti-HGFR / c-Met Reference Antibody (Telisotuzumab vedotin)HumanHGFR / c-MetCHO
NBR-1030NebuSelect™ Anti-IL-3Ra / CD123 Reference Antibody (talacotuzumab-MMAE)HumanIL-3Ra / CD123CHO
NBR-1031NebuSelect™ Anti-KAAG1 Reference Antibody (ADCT-901-MMAE)HumanKAAG1CHO
NBR-1032NebuSelect™ Anti-LIV-1 / SLC39A6 Reference Antibody (Ladiratuzumab vedotin)HumanLIV-1 / SLC39A6CHO
NBR-1033NebuSelect™ Anti-Mesothelin Reference Antibody (anetumab-MMAE)HumanMesothelinCHO
NBR-1034NebuSelect™ Anti-MU5AC Reference Antibody (ensituximab-MMAE)HumanMU5ACCHO
NBR-1035NebuSelect™ Anti-MUC1 Reference Antibody (clivatuzumab-MMAE)HumanMUC1CHO
NBR-1036NebuSelect™ Anti-NaPi2b / SLC34A2 Reference Antibody (Lifastuzumab vedotin)HumanNaPi2b / SLC34A2CHO
NBR-1037NebuSelect™ Anti-NCAM1 / CD56 Reference Antibody (lorvotuzumab-MMAE)HumanNCAM1 / CD56CHO
NBR-1038NebuSelect™ Anti-Nectin-4 Reference Antibody (enfortumab vedotin-ejfv)HumanNectin-4CHO
NBR-1039NebuSelect™ Anti-ROR1 Reference Antibody (Zilovertamab vedotin)HumanROR1CHO
NBR-1040NebuSelect™ Anti-ROR2 Reference Antibody (ozuriftamab vedotin)HumanROR2CHO
NBR-1041NebuSelect™ Anti-Siglec-2 / CD22 Reference Antibody (Pinatuzumab vedotin)HumanSiglec-2 / CD22CHO
NBR-1042NebuSelect™ Anti-Siglec-2 / CD22 Reference Antibody (inotuzumab-MMAE)HumanSiglec-2 / CD22CHO
NBR-1043NebuSelect™ Anti-SLITRK6 Reference Antibody (Sirtratumab vedotin)HumanSLITRK6CHO
NBR-1044NebuSelect™ Anti-TF / Factor III / Tissue Factor / CD142 Reference Antibody (tisotumab vedotin)HumanTF / Factor III / Tissue Factor / CD142CHO
NBR-1045NebuSelect™ Anti-TNFRSF8 / CD30 Reference Antibody (brentuximab vedotin)HumanTNFRSF8 / CD30CHO
NBR-1046NebuSelect™ Anti-TNFSF7 / CD27L / CD70 Reference Antibody (Vorsetuzumab mafodotin)HumanTNFSF7 / CD27L / CD70CHO
NBR-1047NebuSelect™ Anti-TROP2 Reference Antibody (datopotamab deruxtecan)HumanTROP2CHO
NBR-1048NebuSelect™ Anti-TROP2 Reference Antibody (Sacituzumab-MMAE)HumanTROP2CHO


关键词

Praluzatamab Biosimilar; Murlentamab Biosimilar; Enapotamab Biosimilar; Tilvestamab Biosimilar; oregovomab Biosimilar; Sofituzumab Biosimilar; girentuximab Biosimilar; denintuzumab Biosimilar; Polatuzumab Biosimilar; iladatuzumab Biosimilar; labetuzumab Biosimilar; Tusamitamab Biosimilar; zolbetuximab Biosimilar; ulocuplumab Biosimilar; rovalpituzumab Biosimilar; carotuximab Biosimilar; depatuxizumab Biosimilar; Cetuximab Biosimilar; Disitamab Biosimilar; Trastuzumab Biosimilar; patritumab Biosimilar; Patritumab Biosimilar; rosopatamab Biosimilar; farletuzumab Biosimilar; mirvetuximab Biosimilar; ecromeximab Biosimilar; Codrituzumab Biosimilar; Glembatumumab Biosimilar; Indusatumab Biosimilar; Telisotuzumab Biosimilar; talacotuzumab Biosimilar; ADCT-901 Biosimilar; Ladiratuzumab Biosimilar; anetumab Biosimilar; ensituximab Biosimilar; clivatuzumab Biosimilar; Lifastuzumab Biosimilar; lorvotuzumab Biosimilar; enfortumab Biosimilar; Zilovertamab Biosimilar; ozuriftamab Biosimilar; Pinatuzumab Biosimilar; inotuzumab Biosimilar; Sirtratumab Biosimilar; tisotumab Biosimilar; brentuximab Biosimilar; Vorsetuzumab Biosimilar; datopotamab Biosimilar; Sacituzumab Biosimilar; Praluzatamab 生物类似药; Murlentamab 生物类似药; Enapotamab 生物类似药; Tilvestamab 生物类似药; oregovomab 生物类似药; Sofituzumab 生物类似药; girentuximab 生物类似药; denintuzumab 生物类似药; Polatuzumab 生物类似药; iladatuzumab 生物类似药; labetuzumab 生物类似药; Tusamitamab 生物类似药; zolbetuximab 生物类似药; ulocuplumab 生物类似药; rovalpituzumab 生物类似药; carotuximab 生物类似药; depatuxizumab 生物类似药; Cetuximab 生物类似药; Disitamab 生物类似药; Trastuzumab 生物类似药; patritumab 生物类似药; Patritumab 生物类似药; rosopatamab 生物类似药; farletuzumab 生物类似药; mirvetuximab 生物类似药; ecromeximab 生物类似药; Codrituzumab 生物类似药; Glembatumumab 生物类似药; Indusatumab 生物类似药; Telisotuzumab 生物类似药; talacotuzumab 生物类似药; ADCT-901 生物类似药; Ladiratuzumab 生物类似药; anetumab 生物类似药; ensituximab 生物类似药; clivatuzumab 生物类似药; Lifastuzumab 生物类似药; lorvotuzumab 生物类似药; enfortumab 生物类似药; Zilovertamab 生物类似药; ozuriftamab 生物类似药; Pinatuzumab 生物类似药; inotuzumab 生物类似药; Sirtratumab 生物类似药; tisotumab 生物类似药; brentuximab 生物类似药; Vorsetuzumab 生物类似药; datopotamab 生物类似药; Sacituzumab 生物类似药; 科研级 Praluzatamab; 科研级 Murlentamab; 科研级 Enapotamab; 科研级 Tilvestamab; 科研级 oregovomab; 科研级 Sofituzumab; 科研级 girentuximab; 科研级 denintuzumab; 科研级 Polatuzumab; 科研级 iladatuzumab; 科研级 labetuzumab; 科研级 Tusamitamab; 科研级 zolbetuximab; 科研级 ulocuplumab; 科研级 rovalpituzumab; 科研级 carotuximab; 科研级 depatuxizumab; 科研级 Cetuximab; 科研级 Disitamab; 科研级 Trastuzumab; 科研级 patritumab; 科研级 Patritumab; 科研级 rosopatamab; 科研级 farletuzumab; 科研级 mirvetuximab; 科研级 ecromeximab; 科研级 Codrituzumab; 科研级 Glembatumumab; 科研级 Indusatumab; 科研级 Telisotuzumab; 科研级 talacotuzumab; 科研级 ADCT-901; 科研级 Ladiratuzumab; 科研级 anetumab; 科研级 ensituximab; 科研级 clivatuzumab; 科研级 Lifastuzumab; 科研级 lorvotuzumab; 科研级 enfortumab; 科研级 Zilovertamab; 科研级 ozuriftamab; 科研级 Pinatuzumab; 科研级 inotuzumab; 科研级 Sirtratumab; 科研级 tisotumab; 科研级 brentuximab; 科研级 Vorsetuzumab; 科研级 datopotamab; 科研级 Sacituzumab; Praluzatamab; Murlentamab; Enapotamab; Tilvestamab; oregovomab; Sofituzumab; girentuximab; denintuzumab; Polatuzumab; iladatuzumab; labetuzumab; Tusamitamab; zolbetuximab; ulocuplumab; rovalpituzumab; carotuximab; depatuxizumab; Cetuximab; Disitamab; Trastuzumab; patritumab; Patritumab; rosopatamab; farletuzumab; mirvetuximab; ecromeximab; Codrituzumab; Glembatumumab; Indusatumab; Telisotuzumab; talacotuzumab; ADCT-901; Ladiratuzumab; anetumab; ensituximab; clivatuzumab; Lifastuzumab; lorvotuzumab; enfortumab; Zilovertamab; ozuriftamab; Pinatuzumab; inotuzumab; Sirtratumab; tisotumab;  brentuximab; Vorsetuzumab; datopotamab; Sacituzum

发布时间:2024-12-22

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