
【Introduction】
Product Name: Human SLAMF7 / CS1 Antibody (AzintuxizumAb, Research Use)
Catalog Number: NBR-0872
Target Name: SLAMF7 / CS1
Trade Name: AzintuxizumAb
Antibody Drug Description: Azintuxizumab is a SLAMF7 targeting antibody-drug conjugate (ADC). Azintuxizumab consists of a SLAMF7-targeted mAb and a monomethyl auristatin E (MMAE) via a cathepsin B-cleavable peptide linker. Azintuxizumab has the potential for the research of multiple myeloma.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: SLAMF7
Synonyms: 19A; CD319; CRACC; CS1
Target Description: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo-or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response.
Ensembl: ENSG00000026751
Uniprot: Q9NQ25