【Introduction】
Product Name: Human ALX Antibody (Enapotamab, Research Use)
Catalog Number: NBR-0001
Target Name: AXL
Trade Name: Enapotamab
Antibody Drug Description: Enapotamab vedotin is an AXL targeted Antibody-Drug Conjugate (ADC) in which the monoclonal antibody is conjugated to the antimitotic drug monomethyl auristatin E. AXL is a signaling molecule overexpressed in several hematologic and solid malignancies.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: AXL
Synonyms: ARK; JTK11; Tyro7; UFO
Target Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation.
Ensembl: ENSG00000167601
Uniprot: P30530