Product Name: Human Integrin a2b3 (ITGA2 & ITGB3) Antibody (Tadocizumab, Research Use)
Catalog Number: NBR-0879
Target Name: Integrin a2b3 (ITGA2 & ITGB3)
Trade Name: Tadocizumab
Antibody Drug Description: Tadocizumab (C4G1; YM-337) is a humanized monoclonal antibody tageting integrin αIIbβ3. Tadocizumab has antiplatelet and antithrombotic effects, and can be used for cardiovascular disease research. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: ITGA2 & ITGB3
Synonyms: CD49B; CD61; GP3A; GPIIIa
Target Description: Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. 
Ensembl:  ENSG00000164171; ENSG00000259207
Uniprot:  P17301; P05106