Product Name: Human TBFbR2 Antibody (LY3022859, Research Use)
Catalog Number: NBR-0882
Target Name: TBFbR2
Trade Name: LY3022859
Antibody Drug Description: LY3022859 is an anti-TGFβRII IgG1 monoclonal antibody that inhibits receptor-mediated signaling activation. The primary objective of this phase I study was to determine a phase II dose in patients with advanced solid tumors. Secondary objectives were to assess safety and pharmacokinetics (PK). Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name:  TGFBR2
Synonyms: MFS2; TBR-ii; TBRII
Target Description: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3.
Ensembl: ENSG00000163513
Uniprot:  P37173