Product Name: Human TIGIT Antibody (Etigilimab, Research Use)
Catalog Number: NBR-0889
Target Name: TIGIT
Trade Name: Etigilimab
Antibody Drug Description: Etigilimab is an IgG1 monoclonal antibody which binds to the human TIGIT receptor on immune cells with a goal of improving the activation and effectiveness of T-cell and NK cell anti-tumor activity. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name:  TIGIT
Synonyms: DKFZp667A205; FLJ39873; VSIG9; VSTM3
Target Description: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Ensembl:  ENSG00000181847
Uniprot: Q495A1