【Introduction】
Product Name: Human Tau Antibody (Tilavonemab, Research Use)
Catalog Number: NBR-0892
Target Name: Tau
Trade Name: Tilavonemab
Antibody Drug Description: Tilavonemab (ABBV-8E12) is amonoclonal antibody that binds tothe N-terminus of human tau. Weassessed the safety and efficacy oftilavonemab for the treatment ofprogressive supranuclear palsy.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: MAPT
Synonyms: DDPAC; FLJ31424; FTDP-17; MAPTL; MGC138549; MSTD; MTBT1; MTBT2; PPND; PPP1R103; tau
Target Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity . The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both.
Ensembl: ENSG00000186868
Uniprot: P10636